Darcy A Thompson is an Associate Professor of pediatrics at the University of Colorado
School of Medicine. Her main research seeks to address early childhood obesity in
low-income children. She works in the Lifestyle Medicine clinic at Children’s ...
Aim: To compare medication adherence, discontinuation and glycemic control in patients
receiving albiglutide versus liraglutide. Patients & methods: Administrative claims data and glycated hemoglobin (HbA1c) results were analyzed from a sample of adult ...
Aim: An indirect comparison of ustekinumab versus vedolizumab in patients with active
moderate-to-severe Crohn's disease who were nonresponsive or intolerant to previous
TNF-antagonist therapy. Methods: A systematic review was performed in Medline via ...
Aim: We estimate the impact of the FOCUS trial, which concluded that hip surgery patients
with hemoglobin values above 8 g/dl do not benefit from routine transfusions, on transfusion
rates. Methods: We evaluated trends in transfusion rates using ...
Aim: Compare medication utilization, costs and healthcare resource use in schizophrenia
patients with substance-related disorders initiated on once-monthly paliperidone palmitate
(PP1M) or an oral atypical antipsychotic (OAA). Materials & methods: Data ...
Up to 30% of patients taking antipsychotics may develop tardive dyskinesia (TD). Recent
evidence-based recommendations demonstrate an unmet need for effective TD management.
This systematic review was designed to update the evidence for TD treatment, ...
Chronic dermal ulcers affect approximately 2.4–4.5 million people in the USA and are
associated with loss of function, decreased quality of life and significant economic
burden. Debridement is a critical component of wound care involving removal of ...
Spotlight Article Series: CER and PCOR – Enhancing uptake and use by patients, clinicians
and payers – Review
The term comparative effectiveness research (CER) took center stage with passage of
the American Recovery and Reinvestment Act (2009). The companion US$1.1 billion in
funding prompted the launch of initiatives to train the scientific workforce capable
of ...
Evidence from comparative effectiveness research (CER) and patient-centered outcomes
research (PCOR) studies are increasingly available in the literature. However, there
remain opportunities to better integrate that evidence into decision-making. An ...
The goal of comparative effectiveness research (CER) and patient-centered outcomes
research (PCOR) is to improve health outcomes by providing stakeholders with evidence
directly relevant to decision making. In January 2017, the Pharmaceutical Research
...