Volume 6•Issue 7

Aim: To develop a prognostic score for primary breast cancer patients integrating conventional predictors and the novel biomarker CHAC1 to aid adjuvant chemotherapy decisions. Patients & methods: A prognostic score for overall survival was developed ...

Aim: To assess the resource use and associated costs of treating patients with metastatic prostate cancer with a focus on skeletal-related events (SREs). Methods: We performed a bottom-up cost of illness study in The Netherlands. Results: A total of 136 ...

Aim: Can focusing the adverse events search to patients with poor patient-reported outcome help in targeting adverse event detection? Patients & methods: Coronary artery revascularization patients of the Kuopio University Hospital from June 2012 to ...

Aim: Health technology assessment (HTA) is a tool to help the decision-making process. The aim is to describe methods and processes used in the reimbursement decision making for drug-eluting stents (DES) in four different settings. Methods: DES as a ...

Aim: The aim of the systematic review and meta-analysis was to assess the efficacy and safety of ustekinumab in the induction therapy of anti-TNF-α failure patients with Crohn's disease. Methods: A systematic literature search was conducted in Medline (...

Aim: To assess heterogeneity in adherence to medications in two example comparative effectiveness research studies. Patients & methods: We analyzed data from commercially insured patients initiating a statin or anticoagulant during 2005–2012. We ...

Indacaterol/glycopyrronium has been the first long-acting β₂-agonist (LABA)/long-acting muscarinic antagonist (LAMA) fixed-dose combination to be approved as a maintenance treatment in chronic obstructive pulmonary disease patients. Comparative ...