In this update, we examine the growing potential of synthetic data in addressing data
access challenges for health technology assessment. We explore studies evaluating
synthetic data as external control arms in clinical trials and the application of
...
In this update, we cover the evolving health technology assessment process in Australia
and also examine how commercial health plans in the US influence patient access to
treatments.
Aim: This 2023 online survey assessed the management of patients with iron deficiency
anemia/iron deficiency without anemia (IDA/IDWA) in Italy. Materials & methods: The study used the patient’s perspective to examine care pathways used to manage
IDA/...
Aim: This study aims to assess the cost-effectiveness of three major programmed death-ligand
1 (PD-L1) immunohistochemistry (IHC) testing assays in guiding immunotherapy for patients
with advanced non-small-cell lung cancer (NSCLC) in China, and to ...
Aim: The optimal management strategies for spontaneous intracerebral hemorrhage in the
basal ganglia region are still controversial. The purpose of the present study is
to evaluate the clinical benefits of craniotomy, minimally invasive puncture and ...
Aim: To describe real-world adherence, treatment utilization, vaso-occlusive crises (VOC)
and economic outcomes in patients with sickle cell disease (SCD) with recurrent VOC
treated with L-glutamine, voxelotor or crizanlizumab in the US. Materials & ...
Aim: To assess the predictive effect of threshold deviations for multiple liver biomarkers
on negative clinical outcomes, including hepatic decompensation, liver transplantation,
and death in patients with primary biliary cholangitis (PBC) using ...
Aim: We compared the effects of nefecon, an oral targeted-release budesonide formulation,
and sparsentan, an oral, dual endothelin-angiotensin receptor antagonist, on estimated
glomerular filtration rate (eGFR) in patients with immunoglobulin A ...
Aim: Pimavanserin (PIM) is the only US FDA-approved atypical antipsychotics (AAPs) for
the treatment for hallucinations and delusions associated with Parkinson’s disease
psychosis (PDP). In addition to demonstrating symptom improvements in clinical ...
Patient and public involvement in health technology assessment (HTA) has progressed
from best practice to policy requirement, yet communication barriers persist. This
perspective explores how plain language summaries (PLSs) and summaries of information
...