Real-world healthcare resource utilization and costs of weekly versus every-2-week cetuximab in metastatic colorectal cancer
Publication: Journal of Comparative Effectiveness Research
Abstract
Aim: To compare healthcare resource utilization (HRU) and healthcare costs (HC) for every-2-week (Q2W) versus weekly (Q1W) cetuximab in metastatic colorectal cancer (mCRC). Patients & methods: Patients with mCRC receiving cetuximab plus chemotherapy in a line-agnostic setting. Cohort study of patients with mCRC treated with cetuximab and chemotherapy in IBM MarketScan. Analyses were weighted by inverse probability of treatment based on propensity score. Results: HRU was numerically lower with the Q2W versus Q1W regimen (weighted mean, 8.1 vs 9.5 encounters per-patient-per-month). The weighted average of HC was $17,653 and $16,469 per-patient-per-month for the Q2W and Q1W regimens, respectively; the difference between regimens decreased when restricting to CRC-related claims. Conclusion: HRU was lower and HC were similar between the Q2W and Q1W regimens.
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Pages: 353 - 364
PubMed: 33502247
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© 2021 Merck KGaA, Darmstadt, Germany. This work is licensed under the Attribution-NonCommercial-NoDerivatives 4.0 Unported License
History
Received: 27 October 2020
Accepted: 16 December 2020
Published online: 27 January 2021
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Real-world healthcare resource utilization and costs of weekly versus every-2-week cetuximab in metastatic colorectal cancer. (2021) Journal of Comparative Effectiveness Research. DOI: 10.2217/cer-2020-0232
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