Facilitators and barriers to successful recruitment into a large comparative effectiveness trial: a qualitative study
Publication: Journal of Comparative Effectiveness Research
Abstract
Background: Recruitment of participants into research studies, especially individuals from minority groups, is challenging; lack of diversity may lead to biased findings. Aim: To explore beliefs about research participation among individuals who were approached and eligible for the GRADE study. Methods: In-depth qualitative telephone interviews with randomized participants (n = 25) and eligible individuals who declined to enroll (n = 26). Results: Refusers and consenters differed in trust and perceptions of risk, benefits and burden of participation. Few participants understood how comparative effectiveness research differed from other types of trials; however, some features of comparative effectiveness research were perceived as lower risk. Conclusion: We identified facilitators and addressable barriers to participation in research studies.
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Pages: 815 - 826
PubMed: 31368793
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© 2019 Future Medicine Ltd.
History
Received: 11 January 2019
Accepted: 26 April 2019
Published online: 1 August 2019
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Facilitators and barriers to successful recruitment into a large comparative effectiveness trial: a qualitative study. (2019) Journal of Comparative Effectiveness Research. DOI: 10.2217/cer-2019-0010
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