Patterns and association of vaccination among adults with a history of cancer in the USA: a population-based study
Publication: Journal of Comparative Effectiveness Research
Abstract
Aim: To assess the association of vaccination status among adults with history of cancer in a population-based cohort in the USA. Materials & methods: National Health Interview Survey datasets (2008–2018) have been accessed and information about the patterns and associations of the following vaccinations were collected (influenza vaccination, pneumococcal vaccination, hepatitis B vaccination, hepatitis A vaccination and shingles vaccination). Association of different sociodemographic variables with each of the above types of vaccination was studied through multivariable logistic regression analysis. Results: Private health insurance (vs no private insurance) was associated with higher percentages of recommended vaccination (influenza vaccination: 65 vs 59.7%; pneumococcal vaccination: 74.9 vs 68.8%; hepatitis B vaccination: 22.9 vs 19.3%; hepatitis A vaccination: 10.1 vs 8.6%; shingles vaccination: 33.8 vs 26.7%; p < 0.001 for all comparisons). Within multivariable logistic regression analyses, African American race, lower education and lower income were associated with less probability of adherence to recommended vaccination (for influenza vaccination; odds ratio (OR) for black race vs white race: 0.785; 95% CI: 0.717–0.859; OR for ≤high school vs >high school education: 0.763; 95% CI: 0.723–0.805; OR for income ≤US$45,000 vs >US$45,000: 0.701; 95% CI: 0.643–0.764). Conclusion: There is evidence of socio-economic disparities in adherence to recommended vaccination among this cohort of cancer survivors in the USA. More efforts need to be done to ensure that recommended vaccination is being delivered to all cancer survivors in need (including enhancing coverage and awareness to under-represented groups of the society).
Formats available
You can view the full content in the following formats:
References
Papers of special note have been highlighted as: • of interest
1.
Shah MK, Kamboj M. Immunizing cancer patients: which patients? Which vaccines? When to give? Oncology (Williston Park) 32(5), 254–258 c253 (2018).
2.
General recommendations on immunization – recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm. Rep. 60(2), 1–64 (2011). [CDC report].
3.
Bitterman R, Eliakim-Raz N, Vinograd I, Zalmanovici Trestioreanu A, Leibovici L, Paul M. Influenza vaccines in immunosuppressed adults with cancer. Cochrane Database Syst. Rev. 2, Cd008983 (2018).
4.
Toleman MS, Herbert K, Mccarthy N, Church DN. Vaccination of chemotherapy patients – effect of guideline implementation. Support. Care Cancer 24(5), 2317–2321 (2016).
5.
Vollaard A, Schreuder I, Slok-Raijmakers L, Opstelten W, Rimmelzwaan G, Gelderblom H. Influenza vaccination in adult patients with solid tumours treated with chemotherapy. Eur. J. Cancer 76, 134–143 (2017).
6.
Loulergue P, Mir O, Alexandre J, Ropert S, Goldwasser F, Launay O. Low influenza vaccination rate among patients receiving chemotherapy for cancer. Ann. Oncol. 19(9), 1658–1658 (2008).
7.
Pollyea DA, Brown JM, Horning SJ. Utility of influenza vaccination for oncology patients. J. Clin. Oncol. 28(14), 2481–2490 (2010).
8.
Centers for Disease Control & Prevention. Vaccines by disease (2021). www.cdc.gov/vaccines/vpd/vaccines-diseases.html
9.
Centers for Disease Control & Prevention. National Health Interview Survey (2021). www.cdc.gov/nchs/nhis/index.htm
10.
Centers for Disease Control & Prevention. Vaccines by disease (2021). www.cdc.gov/vaccines/vpd/vaccines-diseases.html
11.
Siegel RL, Miller KD, Jemal A. Cancer statistics, 2019. CA Cancer J. Clin. 69(1), 7–34 (2019).
12.
Abdel-Rahman O. Socioeconomic predictors of suicide risk among cancer patients in the United States: a population-based study. Cancer Epidemiol. 63, 101601 (2019).
• The impact of socio-economic variables on the risk of suicide was assessed.
13.
Abdel-Rahman O. Outcomes of nonmetastatic colon cancer patients in relationship to socioeconomic status: an analysis of SEER census tract-level socioeconomic database. Int. J. Clin. Oncol. 24(12), 1582–1587 (2019).
14.
Abdel-Rahman O. Impact of NCI socioeconomic index on the outcomes of nonmetastatic breast cancer patients: analysis of SEER census tract-level socioeconomic database. Clin. Breast Cancer 19(6), e717–e722 (2019).
15.
Liao CY, Mott DA, Ford JH II, Look KA, Hayney MS. Influenza vaccination rates and location for receiving the influenza vaccination among older adult medicare beneficiaries. J. Am. Pharm. Assoc. (2003) (2021) (Epub ahead of print).
16.
Williams WW, Lu PJ, O'Halloran A et al. Surveillance of vaccination coverage among adult populations – United States, 2015. MMWR Surveill. Summ. 66(11), 1–28 (2017).
17.
Racial background and health behaviors among adults with cancer in Canada; results from a National Survey. J. Natl Cancer Comp. Network (In Press).
18.
Loehrer AP, Chang GJ. Implications of the Affordable Care Act on surgery and cancer care. Surg. Oncol. Clin. N. Am. 27(4), 603–614 (2018).
19.
Lu Y, Jackson BE, Gehr AW et al. Affordable Care Act and cancer stage at diagnosis in an underserved population. Prev. Med. 126, 105748 (2019).
20.
Ward EM, Flowers CR, Gansler T, Omer SB, Bednarczyk RA. The importance of immunization in cancer prevention, treatment, and survivorship. CA Cancer J. Clin. 67(5), 398–410 (2017).
Information & Authors
Information
Published In
Pages: 899 - 907
PubMed: 34114478
Copyright
© 2021 Future Medicine Ltd.
History
Received: 10 November 2020
Accepted: 10 May 2021
Published online: 11 June 2021
Keywords:
Topics
Authors
Metrics & Citations
Metrics
Article Usage
Article usage data only available from February 2023. Historical article usage data, showing the number of article downloads, is available upon request.
Citations
How to Cite
Patterns and association of vaccination among adults with a history of cancer in the USA: a population-based study. (2021) Journal of Comparative Effectiveness Research. DOI: 10.2217/cer-2020-0251
Export citation
Select the citation format you wish to export for this article or chapter.
Citing Literature
- Alberto Giuseppe Agostara, Silvia Della Torre, Sara Di Bella, Michela Pelliccione, Paola Candido, Valeria Smiroldo, Davide Toniolo, Francesca Zannier, Roberto Bollina, Enhancing Herpes Zoster Vaccination Rates Among Oncology Outpatients: Impact of an In-House Vaccination Initiative, Cancers, 10.3390/cancers17213502, 17, 21, (3502), (2025).
- Kavita Renduchintala, Mariana Arevalo, Gabriella Fonseca, Mary Katherine Haver, Clement K. Gwede, Smitha Pabbathi, Shannon M. Christy, Vaccination uptake among post-treatment cancer survivors: A multi-vaccine scoping review, Vaccine, 10.1016/j.vaccine.2024.05.043, 42, 22, (125995), (2024).
