The use of real-world effectiveness measurements in clinical settings at Helsinki University Hospital: a systematic literature review
Publication: Journal of Comparative Effectiveness Research
Abstract
Aim: Patient reported outcomes collected alongside clinical trials do not reflect real-world effectiveness (RWE). This review assessed the use of RWE measurements in routine clinical treatment and the instruments applied to collect that data. Materials & methods: The RWE articles published from HUS (Helsinki University Hospital) were extracted from several databases. Results: Out of 170 eligible articles, generic health-related quality of life instruments were used in 87 (51.2%) and disease-specific health-related quality of life instruments in 58 (34.1%) articles as a primary measurement. Most of the articles pertained to surgery, gynecology and pediatric surgery. Conclusion: The number of articles assessing RWE is very limited compared with all the articles published from HUS. Thus, we still have limited information about the effectiveness of the treatment in real life.
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References
Papers of special note have been highlighted as: • of interest; •• of considerable interest
1.
Helsinki University Hospital (2019). www.hus.fi
2.
Drummond MF, Sculpher MJ, Claxton K, Stoddart GL, Torrance GW. Methods for the Economic Evaluation of Health Care Programmes (4th Edition). Oxford University Press, Oxford, UK, 20–73 (2015).
•• Provides essential background for the theory of decision making in healthcare.
3.
Gutacker N, Bojke C, Daidone S, Devlin NJ, Parkin D, Street A. Truly inefficient or providing better quality of care? Analyzing the relationship between risk-adjusted hospital costs and patients’ health outcomes. Health Econ. 22(8), 931–947 (2013).
4.
Sintonen H, Pekurinen M, Linnakko E. Terveystaloustiede (Health Economics) (2nd Edition). WSOY, Porvoo, Finland, 45–49 (1997).
•• Provides background for decision making in healthcare especially in Finnish settings.
5.
Drummond MF, McGuire A. Economic Evaluation in Health Care: Merging Theory with Practice. Oxford University Press, Oxford, UK, 25–32 (2001).
• Provides valuable background information for the article.
6.
Nuttall D, Parkin D, Devlin N. Inter-provider comparison of patient-reported outcomes: developing an adjustment to account for differences in patient case mix. Health Econ. 24(1), 41–54 (2015).
• Gives an idea of how case mix should be taken into account while comparing patient-reported outcomes (PROs).
7.
Santana MJ, Feeny D, Weinkauf J et al. The use of patient-reported outcomes becomes standard practice in the routine clinical care of lung–heart transplant patients. Patient Relat. Outcome Meas. 1, 93–105 (2010).
• Gives a nice example of how PROs are used in routine care.
8.
Nelson EC, Eftimovska E, Lind C, Hager A, Wasson J, Lindblad S. Patient reported outcome measures in practice. BMJ 350, g7818 (2015).
• Describes how PROs should be measured.
9.
Malmivaara A. Real-effectiveness medicine-pursuing the best effectiveness in the ordinary care of patients. Ann. Med. 45(2), 103–106 (2013).
•• Presents a concept for real-life effectiveness and was a driving force for this article.
10.
Helsinki University Hospital. HUS Annual report 2017 (2017). www.hus.fi/en/about-hus/Pages/default.aspx
11.
Hytönen M, Hammarén-Malmi S, Myller J et al. Tautikohtaisen elämänlaatumittarin validointi – esimerkkinä nenä- ja sivuontelotautikohtainen SNOT-22 mittari. Duodecim. 133, 1317–1325 (2017).
•• An example of country-specific validation of disease-specific quality of life instrument.
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Published In
Pages: 321 - 326
PubMed: 32141305
Copyright
© 2020 Kati Koskinen, Maija Hytönen & Pirjo Räsänen. This work is licensed under the Attribution-NonCommercial-NoDerivatives 4.0 Unported License
History
Received: 29 October 2019
Accepted: 8 January 2020
Published online: 6 March 2020
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The use of real-world effectiveness measurements in clinical settings at Helsinki University Hospital: a systematic literature review. (2020) Journal of Comparative Effectiveness Research. DOI: 10.2217/cer-2019-0159
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