The availability of routinely collected health data, such as health administrative
data, electronic health records, prescription records and disease registries, has
increased in the information age. This has led to an explosion of reports of ...
Aims: To compare the efficacy and tolerability of daclatasvir and sofosbuvir (DCV + SOF)
versus SOF and ribavirin (SOF + R) and versus peginterferon-alfa plus ribavirin (A/R)
in patients infected with hepatitis C genotype 3. Patients & methods: Clinical ...
Aim: To evaluate overall survival (OS) in unresectable American Joint Committee on Cancer
(AJCC) stage I/II hepatocellular carcinoma (HCC) treated with drug-eluting-bead transarterial
chemoembolization (DEB-TACE) versus best supportive care. Materials & ...
Aim: Assess the comparative effectiveness of two blood pressure (BP) control interventions
for black patients with uncontrolled hypertension. Patients & methods: A total of 845 patients were enrolled in a three-arm cluster randomized trial. On
admission ...
Objectives: To compare the cost-effectiveness of therapy of gastroesophageal reflux disease with
esomeprazole and other proton pump inhibitors (PPIs) in Poland. Materials & methods: Studies comparing esomeprazole with other PPIs in the treatment of ...
Aims: Electronic health records (EHR), containing rich clinical histories of large patient
populations, can provide evidence for clinical decisions when evidence from trials
and literature is absent. To enable such observational studies from EHR in real ...
Policy makers have clearly indicated – through heavy investment in the Patient Centered
Outcomes Research Institute – that reporting outcomes that are meaningful to patients
is crucial for improvement in healthcare delivery and cost reduction. Better ...
Five annual surveys of healthcare decision-makers potentially affected by comparative
effectiveness research (CER) indicate sustained recognition of its importance and
potential impact. Initial expectations of immediate CER impact have over time turned
...
Aim: To compare the effectiveness of primary percutaneous coronary intervention (pPCI)
and fibrinolytic therapy (FL) for the acute management of ST elevation myocardial
infarction (STEMI). Methods: A review of guidelines and PubMed literature comparing ...