Volume 2•Issue 6

David J Ballard, MD, MSPH, PhD, FACP, is the Chief Quality Officer for Baylor Scott & White Health (TX, USA), the largest not-for-profit healthcare system in the state of Texas, founded on 1 October 2013 from the combination of Baylor Health Care System ...

Evaluation of: Vermorken JB, Stohlmacher-Williams J, Davidenko I et al. Cisplatin and fluorouracil with or without panitumumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck (SPECTRUM): an open-label Phase 3 ...

Evaluation of: Cunningham D, Hawkes EA, Jack A et al. Rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisolone in patients with newly diagnosed diffuse large B-cell non-Hodgkin lymphoma: a Phase 3 comparison of dose intensification ...

Aim: Assess the effect of the Drug Effectiveness Review Project’s comparative effectiveness research findings on prescribing behavior independently and in conjunction with a Medicaid preferred drug list. Method: We queried prescription drug claims and ...

Introduction: Generic atypical antipsychotic drugs should be a focus of attention given their expenditure. However, there is a recognized need to tailor treatments. There were no specific measures in Belgium to enhance the prescribing of oral risperidone ...

Many comparative effectiveness research and patient-centered outcomes research studies will need to be observational for one or both of two reasons: first, randomized trials are expensive and time-consuming; and second, only observational studies can ...

Comparative effectiveness research (CER) is defined as an assessment of all available options for a specific medical condition, with intent to estimate effectiveness in specific subpopulations. Medical professionals must receive training in CER, ...

Prostate-specific antigen testing has dramatically increased the incidence of localized prostate cancer. Most men with localized cancer attempt curative therapy, usually with surgery or radiation. However, there is uncertainty about whether and how to ...

Chronic conditions are the most important cause of morbidity, mortality and health expense in the USA. Comparative effectiveness research (CER) seeks to provide evidence supporting the relative value of alternative courses of action. This research often ...

Aim: Heterogeneity of treatment effect (HTE) occurs when patient factors modify a treatment’s effect on health outcomes due to interactions between these factors and the treatment. This article reviews evidence regarding HTE in stage IV prostate cancer (...