Impact of surgical complications on hospital costs and revenues: retrospective database study of Medicare claims
Publication: Journal of Comparative Effectiveness Research
Abstract
Aim: To compare the length of stay, hospital costs and hospital revenues for Medicare patients with and without a subset of potentially preventable postoperative complications after major noncardiac surgery. Materials & methods: Retrospective data analysis using the Medicare Standard Analytical Files, Limited Data Set, 5% inpatient claims files for years 2016–2020. Results: In 74,103 claims selected for analysis, 71,467 claims had no complications and 2636 had one or more complications of interest. Claims with complications had significantly longer length of hospital stay (12.41 vs 3.95 days, p < 0.01), increased payments to the provider ($34,664 vs $16,641, p < 0.01) and substantially higher estimates of provider cost ($39,357 vs $16,158, p < 0.01) compared with claims without complications. This results on average in a negative difference between payments and costs for patients with complications compared with a positive difference for claims without complications (-$4693 vs $483, p < 0.01). Results were consistent across three different cost estimation methods used in the study. Conclusion: Compared with patients without postoperative complications, patients developing complications stay longer in the hospital and incur increased costs that outpace the increase in received payments. Complications are therefore costly to providers and payers, may negatively impact hospital profitability, and decrease the quality of life of patients. Quality initiatives aimed at reducing complications can be immensely valuable for both improving patient outcomes and hospital finances.
Supplementary Material
References
Papers of special note have been highlighted as: • of interest; •• of considerable interest
1.
Patel AS, Bergman A, Moore BW, Haglund U. The economic burden of complications occurring in major surgical procedures: a systematic review. Appl. Health Econ. Health Policy 11(6), 577–592 (2013).
• This systematic review of 38 studies involving major surgeries demonstrates the important economic burden that complications have on healthcare providers. The authors note the considerable heterogeneity between studies with regards to patient populations, outcomes, procedures, and the need for accurate reporting of costs and resource usage to inform hospital decision-making.
2.
Louis M, Johnston SA, Churilov L, Ma R, Christophi C, Weinberg L. Financial burden of postoperative complications following colonic resection: a systematic review. Medicine (Baltimore) 100(27), e26546 (2021).
3.
Ludbrook GL. The hidden pandemic: the cost of postoperative complications. Curr. Anesthesiol. Rep. 12(1), 1–9 (2022).
4.
de la Plaza Llamas R, Hidalgo Vega Á, Latorre Fragua RA et al. The cost of postoperative complications and economic validation of the Comprehensive Complication Index: prospective study. Ann. Surg. 273(1), 112 (2021).
• Provides validation of the Comprehensive Complication Index, which shows strong association with postoperative costs, but also highlights important measures and best practices that could be used by researchers to reduce bias with regards to the handling of complications and costs in these types of studies.
5.
McNelis J, Castaldi M. “The National Surgery Quality Improvement Project” (NSQIP): a new tool to increase patient safety and cost efficiency in a surgical intensive care unit. Patient Saf. Surg. 8, 19 (2014).
6.
Bilimoria KY, Liu Y, Paruch JL et al. Development and evaluation of the Universal ACS NSQIP surgical risk calculator: a decision aid and informed consent tool for patients and surgeons. J. Am. Coll. Surg. 217(5), 833–842.e3 (2013).
7.
Jones RS, Brown C, Opelka F. Surgeon compensation: “Pay for performance,” the American College of Surgeons National Surgical Quality Improvement Program, the Surgical Care Improvement Program, and other considerations. Surgery 138(5), 829–836 (2005).
8.
Gustafsson UO, Scott MJ, Schwenk W et al. Guidelines for perioperative care in elective colonic surgery: enhanced recovery after surgery (ERAS®) Society Recommendations. World J. Surg. 37(2), 259–284 (2013).
9.
Zhou B, Ji H, Liu Y et al. ERAS reduces postoperative hospital stay and complications after bariatric surgery. Medicine (Baltimore) 100(47), e27831 (2021).
10.
Fuchshuber PR, Greif W, Tidwell CR et al. The power of the National Surgical Quality Improvement Program – achieving a zero pneumonia rate in general surgery patients. Perm. J. 16(1), 39–45 (2012).
11.
Hall BL, Hamilton BH, Richards K, Bilimoria KY, Cohen ME, Ko CY. Does surgical quality improve in the American College of Surgeons National Surgical Quality Improvement Program: an evaluation of all participating hospitals. Ann. Surg. 250(3), 363–376 (2009).
12.
Grass F, Slieker J, Jurt J et al. Postoperative ileus in an enhanced recovery pathway – a retrospective cohort study. Int. J. Colorectal Dis. 32(5), 675–681 (2017).
13.
Ripollés-Melchor J, Ramírez-Rodríguez JM, Casans-Francés R et al. Association between use of enhanced recovery after surgery protocol and postoperative complications in colorectal surgery: the postoperative outcomes within enhanced recovery after surgery protocol (POWER) study. JAMA Surg. 154(8), 725–736 (2019).
14.
The International Surgical Outcomes Study group. Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries. Br. J. Anaesth. 117(5), 601–609 (2016).
15.
Dobson GP. Trauma of major surgery: a global problem that is not going away. Int. J. Surg. Lond. Engl. 81, 47–54 (2020).
16.
Fowler AJ, Wan YI, Prowle JR et al. Long-term mortality following complications after elective surgery: a secondary analysis of pooled data from two prospective cohort studies. Br. J. Anaesth. 129(4), 588–597 (2022).
17.
de la Plaza Llamas R, Ramia Ángel JM, Bellón JM et al. Clinical validation of the comprehensive complication index as a measure of postoperative morbidity at a surgical department: a prospective study. Ann. Surg. 268(5), 838 (2018).
18.
Healy MA, Mullard AJ, Campbell DA Jr, Dimick JB. Hospital and payer costs associated with surgical complications. JAMA Surg. 151(9), 823–830 (2016).
•• This study conducted in a single US health system shows that complications increase costs to hospitals and third-party payers, and reduce hospital profit margins.
19.
Pradarelli JC, Healy MA, Osborne NH, Ghaferi AA, Dimick JB, Nathan H. Variation in Medicare expenditures for treating perioperative complications: the cost of rescue. JAMA Surg. 151(12), e163340 (2016).
20.
Eappen S, Lane BH, Rosenberg B et al. Relationship between occurrence of surgical complications and hospital finances. J. Am. Med. Assoc. 309(15), 1599–1606 (2013).
•• This study shows in a single hospital system that occurrence of postsurgical complications was associated with higher contribution margins for patients covered by private insurance and Medicare, but a lower contribution margin for patients covered by Medicaid or who are self-paid.
21.
Semel ME, Lipsitz SR, Funk LM, Bader AM, Weiser TG, Gawande AA. Rates and patterns of death after surgery in the United States, 1996 and 2006. Surgery 151(2), 171–182 (2012).
22.
Mauermann E, Puelacher C, Lurati Buse G. Myocardial injury after noncardiac surgery: an underappreciated problem and current challenges. Curr. Opin. Anaesthesiol. 29(3), 403–412 (2016).
23.
Devereaux PJ, Sessler DI. Cardiac complications in patients undergoing major noncardiac surgery. N. Engl. J. Med. 373(23), 2258–2269 (2015).
24.
Vascular Events in Noncardiac Surgery Patients Cohort Evaluation (VISION) Study Investigators; Spence J, LeManach Y et al. Association between complications and death within 30 days after noncardiac surgery. Can. Med. Assoc. J. 191(30), E830–E837 (2019).
• Highlights the considerable contribution of three complications, namely: major bleeding; myocardial injury after noncardiac surgery; and sepsis to perioperative mortality in noncardiac surgery.
25.
Fleischmann KE, Goldman L, Young B, Lee TH. Association between cardiac and noncardiac complications in patients undergoing noncardiac surgery: outcomes and effects on length of stay. Am. J. Med. 115(7), 515–520 (2003).
26.
U.S. Centers for Medicare & Medicaid Services. Standard analytical files limited data sets 5%, US Department of Health and Human Services (2021). www.cms.gov/Research-Statistics-Data-and-Systems/Files-for-Order/LimitedDataSets/StandardAnalyticalFiles
27.
U.S. Centers for Medicare & Medicaid Services. Get started with Medicare (2022). www.medicare.gov/basics/get-started-with-medicare
28.
Agency for Healthcare Research and Quality. Most frequent operating room procedures performed in U.S. Hospitals, 2003-2012 #186 (2014). www.hcup-us.ahrq.gov/reports/statbriefs/sb186-Operating-Room-Procedures-United-States-2012.jsp
29.
U.S. Centers for Medicare & Medicaid Services. Hospital Readmissions Reduction Program (HRRP) (2023). www.cms.gov/medicare/medicare-fee-for-service-payment/acuteinpatientpps/readmissions-reduction-program
30.
National Bureau of Economic Research. ICD-9-CM to and from ICD-10-CM and ICD-10-PCS crosswalk or general equivalence mappings (2022). www.nber.org/research/data/icd-9-cm-and-icd-10-cm-and-icd-10-pcs-crosswalk-or-general-equivalence-mappings
31.
ICD10data.com. The Web's Free 2022 ICD-10-CM/PCS medical coding reference’ (2022). www.icd10data.com/
32.
Bureau of Labor Statistics Data. Medical care in U.S. city average, all urban consumers, annual averages (2022). www.bls.gov/cpi/factsheets/medical-care.htm
33.
U.S. Centers for Medicare & Medicaid Services. Cost reports, hospital 2552–2010 form (2021). www.cms.gov/Research-Statistics-Data-and-Systems/Downloadable-Public-Use-Files/Cost-Reports/Hospital-2010-form
34.
Asper F. Calculating cost’: cost-to-charge ratios, ResDac. https://resdac.org/sites/datadocumentation.resdac.org/files/Calculating%20Cost%20-%20Cost-to-Charge%20Ratios%20%28Slides%29.pdf
35.
Frank B. Definitions of ‘cost’ in Medicare utilization files, ResDac. https://resdac.org/sites/datadocumentation.resdac.org/files/Definitions%20of%20%27Cost%27%20in%20Medicare%20Utilization%20Files%20%28Slides%29.pdf
36.
Chen LM, Jha AK, Guterman S, Ridgway AB, Orav EJ, Epstein AM. Hospital cost of care, quality of care, and readmission rates: penny wise and pound foolish? Arch. Intern. Med. 170(4), 340–346 (2010).
37.
U.S. Centers for Medicare & Medicaid Services. Acute inpatient prospective payment system (IPPS) final rule data files (2023). www.cms.gov/Medicare/Medicare-Fee-for-Service-Payment/AcuteInpatientPPS
38.
Shwartz M, Young DW, Siegrist R. The ratio of costs to charges: how good a basis for estimating costs? Inq. J. Med. Care Organ Provis. Financ. 32(4), 476–481 (1995).
39.
Taira D, Seto T, Siegrist R, Cosgrove R, Berezin R, Cohen D. Comparison of analytic approaches for the economic evaluation of new technologies alongside multicenter clinical trials. Am. Heart J. 145, 452–458 (2003).
40.
Stey AM, Brook RH, Needleman J et al. Hospital costs by cost center of inpatient hospitalization for Medicare patients undergoing major abdominal surgery. J. Am. Coll. Surg. 220(2), 207 (2015).
41.
Agency for Healthcare Research and Quality. ‘HCUP-US cost-to-charge ratio for inpatient files’ (2022). www.hcup-us.ahrq.gov/db/ccr/ip-ccr/ip-ccr.jsp
42.
Elixhauser A, Steiner C, Harris DR, Coffey RM. Comorbidity measures for use with administrative data. Med. Care 36(1), 8 (1998).
43.
American College of Surgeons. ‘ACS risk calculator – outcome report’ (2022). https://riskcalculator.facs.org/RiskCalculator/Outcome.jsp
44.
Manecke GR, Asemota A, Michard F. Tackling the economic burden of postsurgical complications: would perioperative goal-directed fluid therapy help? Crit. Care 18(5), 566 (2014).
45.
Dencker EE, Bonde A, Troelsen A, Varadarajan KM, Sillesen M. Postoperative complications: an observational study of trends in the United States from 2012 to 2018. BMC Surg. 21(1), 393 (2021).
46.
Pisarska M, Pędziwiatr M, Małczak P et al. Do we really need the full compliance with ERAS protocol in laparoscopic colorectal surgery? A prospective cohort study. Int. J. Surg. 36, 377–382 (2016).
47.
The ERAS Compliance Group. The impact of enhanced recovery protocol compliance on elective colorectal cancer resection: results from an international registry. Ann. Surg. 261(6), 1153 (2015).
48.
Zandomenico JG, Trevisol FS, Machado JA. Compliance with enhanced recovery after surgery (ERAS) protocol recommendations for bariatric surgery in an obesity treatment center. Braz. J. Anesthesiol. Engl. Ed. 73(1), 36–41 (2023).
49.
Kobayashi K, Kawaguchi Y, Schneider M et al. Probability of postoperative complication after liver resection: stratification of patient factors, operative complexity, and use of enhanced recovery after surgery. J. Am. Coll. Surg. 233(3), 357 (2021).
50.
Shen Y, Lv F, Min S et al. Impact of enhanced recovery after surgery protocol compliance on patients' outcome in benign hysterectomy and establishment of a predictive nomogram model. BMC Anesthesiol. 21(1), 289 (2021).
51.
Geruso M, Layton T. Upcoding: evidence from Medicare on squishy risk adjustment. J. Polit. Econ. 128(3), 984–1026 (2020).
52.
Ferver K, Burton B, Jesilow P. The use of claims data in healthcare research. Open Public Health J. 2(1), 11–24 (2009).
53.
Konrad R, Zhang W, Bjarndóttir M, Proaño R. Key considerations when using health insurance claims data in advanced data analyses: an experience report. Health Syst. 9(4), 317–325 (2019).
54.
Horwitz LI, Partovian C, Lin Z et al. Development and use of an administrative claims measure for profiling hospital-wide performance on 30-day unplanned readmission. Ann. Intern. Med. 161(Suppl. 10), S66–S75 (2014).
55.
Agency for Healthcare Research and Quality. Overview of clinical conditions with frequent and costly hospital readmissions by payer, 2018 #278 (2021). https://hcup-us.ahrq.gov/reports/statbriefs/sb278-Conditions-Frequent-Readmissions-By-Payer-2018.jsp
56.
Hoffman GJ, Tilson S, Yakusheva O. The financial impact of an avoided readmission for teaching and safety-net hospitals Under Medicare's hospital readmission reduction program. Med. Care Res. Rev. MCRR 77(4), 324–333 (2020).
57.
Beauvais B, Whitaker Z, Kim F, Anderson B. Is the hospital value-based purchasing program associated with reduced hospital readmissions? J. Multidiscip. Healthc. 15, 1089–1099 (2022).
Information & Authors
Information
Published In
Copyright
© 2023 The Authors. This work is licensed under the Attribution-NonCommercial-NoDerivatives 4.0 Unported License
History
Received: 26 January 2023
Accepted: 16 May 2023
Published online: 23 June 2023
Keywords:
Topics
Authors
Metrics & Citations
Metrics
Article Usage
Article usage data only available from February 2023. Historical article usage data, showing the number of article downloads, is available upon request.
Citations
How to Cite
Impact of surgical complications on hospital costs and revenues: retrospective database study of Medicare claims. (2023) Journal of Comparative Effectiveness Research. DOI: 10.57264/cer-2023-0080
Export citation
Select the citation format you wish to export for this article or chapter.
Citing Literature
- Oluwasegun Akinyemi, Terrence Fullum, Mojisola Fasokun, Oluebubechukwu Eze, Kakra Hughes, Dahai Yue, Craig Scott Fryer, Jie Chen, Kelle White Whilby, Neighborhood socioeconomic status and short-term postoperative complications following metabolic and bariatric surgery, The American Journal of Surgery, 10.1016/j.amjsurg.2026.116953, 257, (116953), (2026).
- Kerem Enen, Senay Karadag Arli, Knowledge levels of nurses on enhanced recovery after surgery during surgical process: A quasi-experimental study, Perioperative Care and Operating Room Management, 10.1016/j.pcorm.2026.100658, 43, (100658), (2026).
- Rachel Sze Jen Goh, Bryan Chong, Sean Kean Ann Phua, Sean Wei Loong Ho, Arthroscopic Treatment Shows Noninferior Outcomes to Open Treatment for Native Glenohumeral Septic Arthritis: A Systematic Review, Arthroscopy, 10.1002/arj.70173, (2026).
- Mahmoud Diaa Hindawi, Abdel-Fattah Kalmoush, Mohamed Gamal Mohamed, Ezzeldin Ahmed Abdelaty, Abdulrahman Faisal Ziada, Waleed Abdelrhman Kotb, Mohamed Mostafa Eisa, Hamdi Elbelkasi, Richard Peter ten Broek, Edward C.T.H. Tan, Andrew W. Kirkpatrick, Role of prophylactic mesh in emergency midline laparotomy: a systematic review and meta-analysis, World Journal of Emergency Surgery, 10.1186/s13017-026-00697-9, 21, 1, (2026).
- Chunpeng Pan, Jiwei Yu, Shuai Huang, Shoulian Wang, Xiaochun Ni, Haibo Wang, Chihao Zhang, Fan Xiao, Association between 12 composite inflammatory indices and postoperative complications in colorectal cancer surgery: a two-center retrospective study, Frontiers in Oncology, 10.3389/fonc.2026.1808454, 16, (2026).
- Annabelle Emery, Rebecca Allam, David Quinn, Helen Sims, Ian-Ju Liang, Bruno Spellanzon, Julia Groot, Adam Aspbury, Harriet Bullough, Leigh Ingham, Justine Archman, Frankie Brown, Oliver J. Perkin, Alec Snow, Max J. Western, The feasibility of implementing and evaluating individualised digital prehabilitation prior to major elective surgery in adults aged ≥ 50 years: the PreActiv intervention, Perioperative Medicine, 10.1186/s13741-026-00663-8, 15, 1, (2026).
- Xuan Xu, Yijun Wang, A Copula-Based Joint Modeling Framework for Hospitalization Costs and Length of Stay in Massive Healthcare Data, Systems, 10.3390/systems14020226, 14, 2, (226), (2026).
- Juan Ramón Acevedo-Peña, Lina Sofía Morón-Duarte, Kelly Rocío Chacón-Acevedo, David Orlando Aguilar Ramírez, Yira Marcela Torres Castro, Sandra Milena Robayo Rodriguez, Andrea Marcela Gonzalez Bello, Adriana Yaneth Avila Reina, Erica Bibiana Gomez Linares, Nancy Yomayusa Gonzalez, Direct healthcare costs associated with reported patient safety incidents in two tertiary hospitals in Colombia, BMC Health Services Research, 10.1186/s12913-026-14212-y, 26, 1, (2026).
- Rawaa M. Jabbar, Ali Azeez Al-Jumaili, Aymen D. Jaafar, Quantifying the direct costs of diabetic retinopathy in a mixed healthcare system: a hospital-based study from governmental and patient perspectives, Cost Effectiveness and Resource Allocation, 10.1186/s12962-026-00717-0, 24, 1, (2026).
- Amrit Khalsa, Julian Peregoff, Ryan W. Turlip, Justus Zemberi, Gustavo Capone, Michelle Kwon, Amanda Moser, Obinna Uzosike, Ziad Hassan, Nathaniel M. Cieplik, Tensae Assefa, Nnaemeka Okorie, David Casper, AI-Assisted, Literature-Informed Development and Retrospective Validation of a Point-Based Surgical Site Infection Risk Calculator for Spine Surgery, Global Spine Journal, 10.1177/21925682251415176, (2026).
- See more
