Handling missing data in propensity score estimation in comparative effectiveness evaluations: a systematic review
Abstract
Aim: Even though systematic reviews have examined how aspects of propensity score methods are used, none has reviewed how the challenge of missing data is addressed with these methods. This review therefore describes how missing data are addressed with propensity score methods in observational comparative effectiveness studies. Methods: Published articles on observational comparative effectiveness studies were extracted from MEDLINE and EMBASE databases. Results: Our search yielded 167 eligible articles. Majority of these studies (114; 68%) conducted complete case analysis with only 53 of them stating this in the methods. Only 16 articles reported use of multiple imputation. Conclusion: Few researchers use correct methods for handling missing data or reported missing data methodology which may lead to reporting biased findings.
Supplementary Material
References
Papers of special note have been highlighted as: • of interest; •• of considerable interest
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© 2017 Lucas Malla.
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Published online: 5 October 2017
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Handling missing data in propensity score estimation in comparative effectiveness evaluations: a systematic review. (2017) Journal of Comparative Effectiveness Research. DOI: 10.2217/cer-2017-0071
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Vincent FLURIN, Michaela FOCA, Laurence FOIX, Marie Pierre FOS, Catherine FRANCOIS-CHERVET, Ulrike FREY, Jean-Louis GAILLARD, Théophile GAILLOT, Vincent GAJDOS, Serge GALLET, Gildas GALLOU, Idris GANIVALA, Caroline GARANDEAU, Antoine GARBARG-CHENON, Yves GARCERA, Claudio GARCIA SANCHEZ, Fabien GARNIER, Eulalie GARRABE, Anne GASCHET, Jean GASCHIGNARD, Géraldine GASCOIN, Joël GAUDELUS, Valérie GAUDUCHON, Martine GAVIGNET, Françoise GEFFROY, Laurent GENIEZ, Emilie GEORGET, Sophie GERARD, Justine GERAUD, Ezat GHOSN, Vannina GIACOBBI MILET, Isabelle GILLES, Yves GILLET, Catherine GIORGI, Florent GIRARD, Juliette GIRARD, Adeline GIRAUDON, Nathan GIROUX, Isabelle GLATZ, Elodie GLEIZE, Sophie GOBET, Annie GOGUELIN, Celine GOISSEN, Alain GOUDEAU, Anne GOUGEON, Pierre GOUMY, François GOURAUD, Frédérique GOURIET, Alain GOUX, Aurélie GRAILLES, Houria GRAINE, Céline GRANCHER, Anna GRANDO, Christelle GRAS-LE-GUEN, Magali GRECO, Bernard GRESSIER, Isabelle GRIMAL, Emmanuel GRIMPREL, Geneviève GRISE, Richard GRUSS, François GUERIN, Sophie GUIBERT, Henriette GUICHARD, Tamazoust GUIDDIR, Pascal GUIET, Vincent GUIGONIS, Julia GUILBERT, Christine GUILLERMET FROMENTIN, Olivier GUILLUY, Corinne GUITTON, Andreas HAAS, Hervé HAAS, Alexandre HABIB, Abdelatif HACHANI, Guilda HACHEM, Sarah HADJADJ, Isabelle HAEGY-DOEHRING, Mahmad HAGE, Mohamed HAGE CHEHADE, Houria HALLAGE, Fazia HALLALEL, Muriel HALNA, Farida HAMDAD, Severine HAOUISEE, Samir HARCHAOUI, Rihad HATAHET, Fréderique HAY, Noureddine HEDJEM, Laure HEES, Annie HEIDT, Véronique HENTGEN, Marie-Christine HERAUD, Christian HERVE, Joelle HEURTE, Emmanuelle HEUSSE, Rachel HEYMAN, Céline HIVERT, Anne-cécile HOCHART, Cécile HOMBROUCK-ALET, Stéphanie HONORÉ, Cosmina HOREA, Nathalie HUBERT, Philippe HUBERT, Frédéric HUET, Nicole HUIN, Hélène HUVENNE, Nourredine IDRES, Patrick IKOUNGA, Tara INGRAO, Jacques IRAKOTOH, Jean Louis JACOB, Coralie JACQUET, Mohamad JALLOUL, Didier JAN, Anne-Christinne JAOUEN, Vincent JARLIER, Pierre-Henri JARREAU, 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