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Commentary
25 February 2022

Health technology assessments and real-world evidence: tell us what you want, what you really, really want

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References

1.
Angelis A, Lange A, Kanavos P. Using health technology assessment to assess the value of new medicines: results of a systematic review and expert consultation across eight European countries. Eur. J. Health Econ. 19(1), 123–152 (2018).
2.
Patel D, Grimson F, Mihaylova E et al. Use of external comparators for health technology assessment submissions based on single-arm trials. Value Health 24(8), 1118–1125 (2021).
4.
CADTH. common drug review – ocrelizumab (2017). https://cadth.ca/ocrelizumab
5.
CADTH. common drug review – tocilizumab (2018). www.cadth.ca/index.php/tocilizumab-3
6.
NICE. Technology appraisal guidance [TA518] – tocilizumab for treating giant cell arteritis (2018). www.nice.org.uk/guidance/ta518
7.
NICE. Technology appraisal guidance [TA585] – ccrelizumab for treating primary progressive multiple sclerosis (2019). www.nice.org.uk/guidance/ta585.
10.
IQWIG. Extract of dossier assessment A17-19 – Alectinib (non-small cell lung cancer) (2017). www.iqwig.de/download/a17-19_alectinib_extract-of-dossier-assessment_v1-0.pdf?rev=185028
11.
Haute Autorité de Santé (HAS). Commission De La Transparence - Tisagenlecleucel (2018). www.has-sante.fr/upload/docs/application/pdf/2018-12/kymriah_ldgcb_pic_ins_avis3_ct17238.pdf
12.
Norwegian Medicines Agency. Single Technology assessment - Tisagenlecleucel (Kymriah) for the treatment of second or later relapsed/refractory diffuse large B cell lymphoma (DLBCL) (2019). https://legemiddelverket.no/Documents/Offentlig%20finansiering%20og%20pris/Metodevurderinger/K/Kymriah_DLBCL_2019.pdf
13.
Macdonald H, Goldacre B. Does the reformed cancer drug fund generate evidence on effectiveness? A cross-sectional analysis on publicly accessible documentation. medRxiv (2020) (Epub ahead of print).
14.
Sammon CJ, Leahy TP, Gsteiger S, Ramagopalan S. Real-world evidence and nonrandomized data in health technology assessment: using existing methods to address unmeasured confounding? J. Comp. Eff. Res. 9(14), 969–972 (2020).
15.
Brown JP, Douglas IJ, Hanif S, Thwaites RMA, Bate A. Measuring the effectiveness of real-world evidence to ensure appropriate impact. Value Health 24(9), 1241–1244 (2021).
16.
Carter P, Laurie GT, Dixon-Woods M. The social licence for research: why care.data ran into trouble. J. Med. Ethics 41(5), 404 (2015).