Variation in prostate surgery costs and outcomes in the USA: robot-assisted versus open radical prostatectomy
Abstract
Aim: To compare perioperative complications, inpatient cost and length of stay between robot-assisted radical prostatectomy (RARP) and open radical prostatectomy (ORP) using National Inpatient Sample data from 2010 to 2015. Patients & methods: A total of 69,009 records with RARP or ORP were analyzed using multivariate logistic regression and generalized linear models. Results: The RARP had superior perioperative outcomes at a higher cost (adjusted mean difference = 2956; 95% CI: $2822–$3090) and shorter length of stay (mean difference = 0.85; 95% CI: 0.81–0.89) compared with ORP. Mean cost of RARP was lowest in urban teaching, private invest-own, high volume and northeast region hospitals and highest for black men. Conclusion: Compared with ORP, RARP had significantly better perioperative outcomes at a higher cost.
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References
Papers of special note have been highlighted as: • of interest; •• of considerable interest
1.
American Cancer Society. Key statistics for prostate cancer (2018). www.cancer.org/cancer/prostate-cancer/about/key-statistics.html.
2.
American Cancer Society. Survival rates for prostate cancer (2017). www.cancer.org/cancer/prostate-cancer/detection-diagnosis-staging/survival-rates.html.
3.
Sanda MG, Cadeddu JA, Kirkby E et al. Clinically localized prostate cancer: AUA/ASTRO/SUO Guideline. Part I: risk stratification, shared decision making, and care options. J. Urol. 199(3), 683–690 (2018).
4.
Kelley WE Jr. The evolution of laparoscopy and the revolution in surgery in the decade of the 1990s. JSLS 12(4), 351–357 (2008).
5.
Finkelstein J, Eckersberger E, Sadri H, Taneja SS, Lepor H, Djavan B. Open versus laparoscopic versus robot-assisted laparoscopic prostatectomy: the European and US experience. Rev. Urol. 12(1), 35–43 (2010).
6.
Leow JJ, Chang SL, Meyer CP et al. Robot-assisted versus open radical prostatectomy: a contemporary analysis of an all-payer discharge database. Eur. Urol. 70(5), 837–845 (2016).
•• Perioperative outcomes, costs comparison between robot-assisted radical prostatectomy (RARP) and open radical prostatectomy (ORP) using Premier hospital database.
7.
Chang SL, Kibel AS, Brooks JD, Chung B. The impact of robotic surgery on the surgical management of prostate cancer in the USA. BJU Int. 115(6), 929–936 (2015).
8.
Yaxley JW, Coughlin GD, Chambers SK et al. Robot-assisted laparoscopic prostatectomy versus open radical retropubic prostatectomy: early outcomes from a randomized controlled Phase III study. Lancet 388(10049), 1057–1066 (2016).
9.
Krambeck AE, Dimarco DS, Rangel LJ et al. Radical prostatectomy for prostatic adenocarcinoma: a matched comparison of open retropubic and robot-assisted techniques. BJU Int. 103(4), 448–453 (2008).
10.
Ficarra V, Novara G, Fracalanza S et al. A prospective, non-randomized trial comparing robot-assisted laparoscopic and retropubic radical prostatectomy in one European institution. BJU Int. 104(4), 534–539 (2009).
11.
Ficarra V, Novara G, Atribani W et al. Retropubic, laparoscopic, and robot-assisted radical prostatectomy: a systematic review and cumulative analysis of comparative studies. Eur. Urol. 55(5), 1037–1063 (2009).
12.
Lowrance WT, Elkin EB, Jacks LM et al. Comparative effectiveness of surgical treatments for prostate cancer: a population-based analysis of postoperative outcomes. J. Urol. 183(4), 1366–1372 (2010).
13.
Hu JC, GU X, Lipstiz SR, Barry MJ et al. Comparative effectiveness of minimally invasive vs. open radical prostatectomy. JAMA 302(14), 1557–1564 (2009).
• Provides ICD-9 diagnosis codes for various perioperative complication.
14.
Liu J-J, Maxwell BG, Panousis P, Chung BI. Perioperative outcomes for laparoscopic and robotic compared with open prostatectomy using the national surgical quality improvement program (NSQIP) database. Urology 82(3), 579–583 (2013).
15.
Trinh QD, Sammon J, Sun M et al. Perioperative outcomes of robot-assisted radical prostatectomy compared with open radical prostatectomy: results from the nationwide inpatient sample. Eur. Urol. 61(4), 679–685 (2012).
•• Perioperative outcomes, cost comparison between RARP and ORP.
16.
Gandaglia G, Sammon JD, Chang SL et al. Comparative effectiveness of robot-assisted and open radical prostatectomy in the postdissemination era. J. Clin. Oncol. 32(14), 1419–1426 (2014).
•• Perioperative outcomes, cost comparison between RARP and ORP.
17.
Hu JH, O'Malley P, Chughtai B et al. Comparative effectiveness of cancer control and survival after robot assisted versus open radical prostatectomy. J. Urol. 197(1), 115–121 (2017).
•• Perioperative outcomes, cost comparison between RARP and ORP.
18.
William SB, D'Amico AV, Weinberg AC, Gu X, Lipsitz SR, Hu JC. Population-based determinants of radical prostatectomy surgical margin positivity. BJU Int. 107(11), 1734–1740 (2011).
19.
Williams SB, Chen MH, D'Amico AV et al. Radical retropubic prostatectomy and robot-assisted laparoscopic prostatectomy: likelihood of positive surgical margin(s). Urology 76(5), 1097–1101 (2010).
20.
Novara G, Ficarra V, Mocellin S et al. Systematic review and meta-analysis of studies reporting oncologic outcomes after robot-assisted radical prostatectomy. Eur. Urol. 62(3), 382–404 (2012).
21.
Tewari A, Sooriakumaran P, Bloch DA, Seshadri-Kreaden U, Herbert AE, Wiklund P. Positive surgical margin and perioperative complication rates of primary surgical treatments for prostate cancer: a systematic review and meta-analysis comparing retropubic, laparoscopic, and robotic prostatectomy. Eur. Urol. 62(1), 1–15 (2012).
22.
Sooriakumaran P, Sirvastavae A, Shariat SF et al. A multinational, multi-institutional study comparing positive surgical margin rates among 22393 open, laparoscopic, and robot-assisted radical prostatectomy patients. Eur. Urol. 66(3), 450–456 (2014).
23.
Lowrance WT, Tarin TV, Shariat SF. Evidence-based comparison of robotic and open radical prostatectomy. ScientificWorldJournal. 10, 2228–2237 (2010).
24.
Bolenz C, Gupta A, Hotze T et al. Cost comparison of robotic, laparoscopic and open radical prostatectomy for prostate cancer. Eur. Urol. 57(3), 453–458 (2010).
25.
Sanda MG, Cadeddu JA, Kirkby E et al. Clinically localized prostate cancer: AUA/ASTRO/SUO Guideline. Part II: recommended approaches and details of specific care options. J. Urol. 199(4), 990–997 (2018).
26.
Seal B, Sullivan SD, Ramsey SD et al. Comparing hospital-based resource utilization and costs for prostate cancer patients with and without bone metastases. Appl. Health Econ. Health Pol. 12(5), 547–557 (2014).
27.
Parsons JK, Chang D. In reply to faulty analysis in study of robotic-assisted minimally invasive radical prostatectomy. JAMA Surg. 150(4), 372 (2015).
28.
Premier Applied Sciences, Premier Inc. Premier Healthcare Database White Paper: data that informs and performs, February 18, 2018 (2018). www.premierinc.com/transforming-healthcare/healthcare-performance-improvement/premier-applied-sciences/.
29.
Agency for Healthcare Research and Quality. HCUP Nationwide inpatient sample (NIS) Healthcare cost and utilization project (HCUP). 2010, 2011. MD, USA. www.hcup-us.ahrq/gov/nisoverview.jsp.
30.
Agency for Healthcare Research and Quality. HCUP Nationwide inpatient sample (NIS) Healthcare cost and utilization project (HCUP). 2012, 2013. MD, USA. www.hcup-us.ahrq/gov/nisoverview.jsp.
31.
Froehner M, Novotny V, Koch R, Leike S, Twelker L, Wirth MP. Perioperative complications after radical prostatectomy: open versus robot-assisted laparoscopic approach. Urol. Int. 90(3), 312–315 (2013).
32.
U.S. Bureau of Labor Statistics. Consumer price index for all urban consumers: hospital and related services [CUUR0000SEMD]. USA: FRED, Federal Reserve Bank of St Louis. https://fred.stlouisfed.org/series/CUUR0000SEMD (2018).
33.
Tyson MD 2nd, Andrews PE, Ferrigni RF, Humphreys MR, Parker AS, Castle EP. Radical prostatectomy trends in the United States: 1998 to 2011. Mayo Clin. Proc. 91(1), 10–16 (2016).
34.
Davis JW, Kreaden US, Gabbert J, Thomas R. Learning curve assessment of robot-assisted radical prostatectomy compared with open-surgery control from the premier perspective database. J. Endourol. 28(5), 560–566 (2014).
35.
Jacobs EFP, Boris R, Masterson TA. Advances in robotic-assisted radical prostatectomy over time. Prostate Cancer 2013, (2013) (Epub ahead of print).
36.
Magheli A, Gonzalgo ML, Su LM et al. Impact of surgical technique (open vs laparoscopic vs robotic-assisted) on pathological and biochemical outcomes following radical prostatectomy: an analysis using propensity score matching. BJU Int. 107(12), 1956–1962 (2011).
37.
van der Schatte Olivier RH, Van't Hullenaar CD, Ruurda JP, Broeders IA. Ergonomics, user comfort, and performance in standard and robot-assisted laparoscopic surgery. Surg. Endosc. 23(6), 1365–1371 (2008).
38.
Samadi DB, Muntner P, Nabizada-Pace F, Brajtbord JS, Carlucci J, Lavery HJ. Improvements in robot-assisted prostatectomy: the effect of surgeon experience and technical changes on oncologic and functional outcomes. J. Endourol. 24(7), 1105–1110 (2010).
39.
Reynolds BR, Bulsara C, Zeps N et al. Exploring pathways towards improving patient experience of robot-assisted radical prostatectomy (RARP): assessing patient satisfaction and attitudes. BJU Int. 121(Suppl. 3), 33–39 (2018).
40.
Cole AP, Leow JL, Chang SL et al. Surgeon and hospital level variation in the costs of robot-assisted radical prostatectomy. J. Urol. 196(4), 1090–1096 (2016).
41.
Moses KA, Orom H, Brasel A, Gaddy J, Underwood W 3rd. Racial/ethnic disparity in treatment for prostate cancer: does cancer severity matter? Urology 99, 76–83 (2017).
42.
Faiena I, Dombrovskiy VY, Modi PK et al. Regional cost variations of robot-assisted radical prostatectomy compared with open radical prostatectomy. Clin. Genitourin. Cancer 13(5), 447–452 (2015).
•• Analysis of cost of radical prostatectomy based on hospital characteristics and region.
43.
Houchens R, Elixhauser A. 2012 National inpatient sample (NIS) comparison report (2015). HCUP methods series report # 2015–04 ONLINE. April 19, 2016. U.S. Agency for Healthcare Research and Quality. www.hcup-us.ahrq.gov/reports/methods/methods.jsp.
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© 2019 Future Medicine Ltd.
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Received: 10 October 2018
Accepted: 23 November 2018
Published online: 8 January 2019
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Variation in prostate surgery costs and outcomes in the USA: robot-assisted versus open radical prostatectomy. (2019) Journal of Comparative Effectiveness Research. DOI: 10.2217/cer-2018-0109
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- Graham R Hale, Mohammed Shahait, David I Lee, Daniel J Lee, Ryan W Dobbs, Measuring Quality of Life Following Robot-Assisted Radical Prostatectomy, Patient Preference and Adherence, 10.2147/PPA.S271447, Volume 15, (1373-1382), (2021).
- Ben Xu, Yi-ji Peng, Guo-zhong Ma, Qian Zhang, A novel “three-port” trocar placement technique for laparoscopic radical prostatectomy, World Journal of Surgical Oncology, 10.1186/s12957-020-02051-y, 18, 1, (2020).
- W. F. Wieland, M. Burger, S. Denzinger, W. Otto, V. N. Pavlov, Radical Prostatectomy: from Open Surgery towards Robotic Laparoscopy, Creative surgery and oncology, 10.24060/2076-3093-2020-10-2-87-93, 10, 2, (87-93), (2020).
- Miao Wang, Yi-feng Yang, Bo-da Guo, Hui-min Hou, Ling-feng Meng, Xuan Wang, Millicent Amankwah, Bao-qiong Liu, Cheng-yue Jin, Ming Liu, Jian-ye Wang, The impact of atrial fibrillation on outcomes in patients undergoing radical prostatectomy, World Journal of Urology, 10.1007/s00345-020-03337-2, 39, 5, (1509-1519), (2020).
- Zaeem Lone, Ahmed A. Hussein, Zhe Jing, Ahmed S. Elsayed, Naif A. Aldhaam, Karen Sniadecki, Khurshid A. Guru, Optimizing the Financial Burden of the Approach to Robot-Assisted Radical Prostatectomy, Journal of Endourology, 10.1089/end.2019.0869, 34, 4, (456-460), (2020).
