Skip to main content
Free access
Editorial
12 July 2017

Deriving more value from RWE to ensure timely access of medicines by patients

First page of PDF

Formats available

You can view the full content in the following formats:

References

1.
De Lusignan S, Crawford L, Munro N. Creating and using real-world evidence to answer questions about clinical effectiveness. J. Innov. Health Inform. 22(3), 368–373 (2015).
2.
Looney W. Real world evidence – from volume to value. Pharmaceutical Executive 36, 10 (2016).
3.
Emilsson L, Lindahl B, Köster M et al. Review of 103 Swedish healthcare registries. J. Intern. Med. 277, 94–136 (2014).
5.
Muka T, Imo D, Jaspers L et al. The global impact of non-communicable diseases on healthcare spending and national income: a systematic review. Eur. J. Epidemiol. 30(4), 251–277 (2015).
6.
Hughes B, Kessler M. The $1 billion real world evidence. IMS Health (2014). www.imshealth.com/files/web/Global/Services/Services%20TL/rwes_breaking_new_ground_d10.pdf.
7.
Czirakym M, Pollock M. Real world evidence studies. Applied Clinical Trials (2015). www.appliedclinicaltrialsonline.com/real-world-evidence-studies?pageID=2.
8.
Sherman RE, Anderson SA, Dal Pan GJ et al. Real-world evidence – what is it and what can it tell us? N. Engl. J. Med. 375(23), 2293–2297 (2016).
9.
Petrova M, Dale J, Fulford BK. Values-based practice in primary care: easing the tensions between individual values, ethical principles and best evidence. Br. J. Gen. Pract. 56(530), 703–709 (2006).
10.
Brown MM, Brown GC. Update on value-based medicine. Curr. Opin. Ophthalmol. 24, 183–189 (2013).
11.
Ludvigsson JF, Andersson E, Ekbom A et al. External review and validation of the Swedish national inpatient register. BMC Public Health 11, 450 (2011).
12.
Trojano T, Tintore M, Montalban X et al. Treatment decisions in multiple sclerosis – insights from real-world observational studies. Nat. Rev. Neurol. 13(2), 105–118 (2017).
13.
Synergus. Where is the best quality real world data regarding heart failure in Europe. https://synergus.com/blog/where-best-quality-real-world-data-regarding-heart-failure-europe.
14.
Anderson SR, Auquier A, Hauck WW et al. Statistical Methods for Comparative Studies: Techniques for Bias Reduction. Wiley & Sons, NJ, USA (2009).
15.
Stel VS, Dekker FW, Zoccali C, Jager KJ. Instrumental variable analysis. Nephrol. Dial. Transplant. 28(7), 1694–1699 (2013).
16.
Garavan T. Global talent management in science-based firms: an exploratory investigation of the pharmaceutical industry during the global downturn. Int. J. Human Res. Management 23, 12 (2012).
17.
Concato J, Shah N, Horwitz RI. Randomized, controlled trials, observational studies, and the hierarchy of research designs. N. Engl. J. Med. 342(25), 1887–1892 (2000).
18.
Thygesen LC, Ersboll AK. When the entire population is the sample: strengths and limitations in register-based epidemiology When the entire population is the sample: strengths and limitations in register-based epidemiology. Eur. J. Epidemiol. 29, 551–558 (2014).
19.
Hall D. Why public–private partnerships don't work. Public Services International (2015). www.world-psi.org/sites/default/files/rapport_eng_56pages_a4_lr.pdf.
20.
Gill JL, Avouac B, Duncombe R et al. The use of real world evidence in the European context: an analysis of key expert opinion. London School of Economics (2016). http://blogs.lse.ac.uk/lseenterprise/files/2016/12/RWE_in_Europe_Paper1.pdf.
21.
Epstein RS, Sidorov J, Lehner JP, Salimi T. Integrating scientific and real-world evidence within and beyond the drug development process. J. Comp. Eff. Res. 1(Suppl. 1), 9–13 (2012).
22.
Garrison L, Neumann P, Erickson P et al. Using real world data for coverage and payment decisions: the ISPOR real-world data task force report. Value Health 10(5), 326–335 (2007).
23.
Pietri G, Masoura P. Market access and reimbursement: the increasing role of real-world evidence. Value Health 17(7), A450–A451 (2014).
24.
Makady M, Ten Ham R, De Boer A et al. Policies for use of real-world data in health technology assessment (HTA): a comparative study of six HTA agencies. Value Health 20(4), 520–532 (2017).
25.
White R. Building trust in real-world evidence and comparative effectiveness research: the need for transparency. J. Comp. Eff. Res. 6(1), 5–7 (2017).
26.
Eichler HG, Baird HG, Barker R et al. From adaptive licensing to adaptive pathways: delivering a flexible life-span approach to bring new drugs to patients. Clin. Pharmacol. Ther. 97(3), 234–246 (2015).