From claims to commercial strategy: Finding actionable insights in rare disease data
Patient-level claims data has become an increasingly important resource for supporting commercial strategy, market access, and evidence generation in rare disease. Yet small patient populations, delayed diagnosis, and inconsistent coding practices mean that even the largest datasets capture only part of the picture. How can organizations use claims data to generate meaningful insights while understanding its limitations?
This question formed the basis of the roundtable discussion "From Claims to Commercial Strategy in Rare Disease: Signal vs Noise" at World Orphan Drug Congress USA 2026. Led by Lucas Paine (Forian), the session explored how manufacturers, advocacy groups, and data providers are using claims data to identify patients, support evidence generation, and inform market access, while highlighting the challenges of patient identification, diagnosis coding, and linked data.
For professionals working in HEOR, RWE, market access, regulatory affairs, and rare disease commercialization, the discussion provides practical perspectives on how claims data can be used to support patient identification, evidence generation, and reimbursement discussions in rare disease.
Read the full Deep Dive here.
About the speaker
Lucas Paine
Director of Life Sciences, Forian
Lucas Paine is Director of Life Sciences at Forian, where he leads commercial engagement and strategic partnerships across the pharmaceutical and biotech sectors. He brings more than 20 years of healthcare and life sciences experience spanning pharmaceutical manufacturing, strategy consulting, and real-world data analytics. Prior to joining Forian in 2021, Lucas held roles at Sanofi and IQVIA, developing expertise in commercial strategy, market insights, and data-driven decision making.
Drawing on experience across both industry and data providers, Lucas helps pharmaceutical organizations leverage claims and real-world data to support commercialization strategies from pre-launch planning through lifecycle management. His work focuses on aligning data assets to business objectives across marketing, market access, patient services, and analytics teams. Lucas is particularly passionate about building collaborative client partnerships that translate complex data into actionable business insights.
Sponsorship for this Deep Dive was provided by Forian.